Max J E, Robin D A, Lindgren S D, Smith W L, Sato Y, Mattheis P J, Stierwalt J A, Castillo C S
Department of Psychiatry, University of Iowa, Iowa City 52242, USA.
J Am Acad Child Adolesc Psychiatry. 1997 Sep;36(9):1278-85. doi: 10.1097/00004583-199709000-00021.
To extend findings regarding predictive factors of psychiatric outcome from the first to the second year after traumatic brain injury (TBI) in children and adolescents.
Subjects were children aged 6 to 14 years at the time they were hospitalized after TBI. The study used a prospective follow-up design. Assessments of preinjury psychiatric, behavioral, adaptive functioning, family functioning and family psychiatric history status were conducted. Severity of injury was assessed by standard clinical scales and neuroimaging was analyzed. The outcome measure was the presence of a psychiatric disorder, not present before the injury ("novel"), during the second year after TBI.
Fifty subjects enrolled, and the analyses focused on 42 subjects followed at 24 months. Severity of injury, preinjury family function, and preinjury lifetime psychiatric history predicted the development of a "novel" psychiatric disorder present in the second year.
These data suggest that there are children, identifiable through clinical assessment, at increased risk for "novel" psychiatric disorders in the second year after TBI.
将儿童和青少年创伤性脑损伤(TBI)后第一年精神科预后预测因素的研究结果扩展至第二年。
研究对象为TBI住院时年龄在6至14岁的儿童。本研究采用前瞻性随访设计。对伤前精神状态、行为、适应性功能、家庭功能及家族精神病史状况进行评估。通过标准临床量表评估损伤严重程度,并分析神经影像学检查结果。结局指标为TBI后第二年出现的伤前不存在的精神障碍(“新发”)。
共纳入50名受试者,分析聚焦于42名随访24个月的受试者。损伤严重程度、伤前家庭功能及伤前终生精神病史可预测第二年出现的“新发”精神障碍。
这些数据表明,通过临床评估可识别出TBI后第二年发生“新发”精神障碍风险增加的儿童。