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正常男性和良性前列腺增生患者血浆中的性激素结合球蛋白

Sex-hormone-binding globulin in the plasma of normal men and patients with benign prostatic hypertrophy.

作者信息

Minguell J J, Merino J, Valladares L E, Troncoso S

出版信息

Arch Androl. 1979;3(2):167-71. doi: 10.3109/01485017908985065.

Abstract

Sex-hormone-binding globulin (SHBG) was measured in the plasma of normal men aged 30--50 yr, normal men 50--70 yr of age, and men 50--70 yr of age suffering from benign prostatic hypertrophy (BPH). The level of binding proteins in normal "young" men decreased approximately 45% in normal "older" men. A 100% rise was observed in BPH patients as compared to normal older men. This increase seemed to be related to a rise in SHBG and also to the appearance of binding species of smaller molecular weight than that of SHBG.

摘要

在30至50岁的正常男性、50至70岁的正常男性以及患有良性前列腺增生(BPH)的50至70岁男性的血浆中测量了性激素结合球蛋白(SHBG)。正常“年轻”男性中结合蛋白的水平在正常“年长”男性中下降了约45%。与正常年长男性相比,BPH患者中观察到该水平升高了100%。这种升高似乎与SHBG的升高以及分子量比SHBG小的结合物种的出现有关。

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