Acton J, Salmon J F, Scholtz R
Department of Ophthalmology, Groote Schuur Hospital and University of Cape Town, South Africa.
J Cataract Refract Surg. 1997 Jul-Aug;23(6):930-4. doi: 10.1016/s0886-3350(97)80255-6.
To evaluate long-term intraocular pressure (IOP) control after extracapsular cataract extraction (ECCE) with posterior chamber intraocular lens (IOL) implantation in patients with primary angle-closure glaucoma.
Ophthalmology Department, Groote Schuur Hospital, Cape Town, South Africa.
This retrospective study comprised 17 patients (19 eyes) with primary angle-closure glaucoma who had ECCE and posterior chamber IOL implantation. Four presented initially with acute glaucoma, 5 with subacute angle-closure glaucoma, and 8 (10 eyes) with chronic angle-closure glaucoma. In all, less than half the circumference of the angle was permanently closed. The drainage angle was evaluated preoperatively and postoperatively to monitor changes in the amount of angle closure. Intraocular pressure was measured in the early and late postoperative periods.
On the first postoperative day, mean IOP was 17.2 mm Hg, although 5 patients (26%) had an IOP rise above 21 mm Hg despite the use of perioperative topical pilocarpine gel. After a mean follow-up of 19 months, IOP remained below 22 mm Hg without medication in 13 eyes (68%) and with topical medication in 5 eyes (26%). Mean number of glaucoma medications was reduced from 1.5/eye preoperatively to 0.5/eye postoperatively.
Cataract extraction with IOL implantation resulted in good long-term IOP control in patients with primary angle-closure glaucoma, suggesting that combined cataract and trabeculectomy surgery may not be necessary to achieve long-term IOP control in these patients.
评估原发性闭角型青光眼患者行白内障囊外摘除术(ECCE)联合后房型人工晶状体(IOL)植入术后的长期眼压(IOP)控制情况。
南非开普敦格罗特舒尔医院眼科。
这项回顾性研究纳入了17例(19只眼)原发性闭角型青光眼患者,这些患者均接受了ECCE及后房型IOL植入术。其中4例最初表现为急性青光眼,5例为亚急性闭角型青光眼,8例(10只眼)为慢性闭角型青光眼。总之,房角周长不到一半被永久性关闭。术前和术后评估引流房角,以监测房角关闭程度的变化。在术后早期和晚期测量眼压。
术后第1天,平均眼压为17.2 mmHg,尽管5例患者(26%)在围手术期使用了局部毛果芸香碱凝胶,但眼压仍升高至21 mmHg以上。平均随访19个月后,13只眼(68%)无需药物治疗眼压仍低于22 mmHg,5只眼(26%)需局部药物治疗。青光眼药物的平均使用数量从术前的每只眼1.5种减少到术后的每只眼0.5种。
白内障摘除联合IOL植入术可使原发性闭角型青光眼患者获得良好的长期眼压控制,这表明对于这些患者,可能无需联合白内障和小梁切除术来实现长期眼压控制。