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胸主动脉横断:发病率的年龄特异性差异及可能原因。

Transected thoracic aorta: age-specific differences in incidence and possible reasons.

作者信息

Tripp H F, Robicsek F, Thomason M, Thubrikar M

机构信息

Department of Thoracic and Cardiovascular Surgery, Carolinas Heart Institute, Carolinas Medical Center, North Carolina, USA.

出版信息

Cardiovasc Surg. 1997 Jun;5(3):291-4. doi: 10.1016/s0967-2109(97)00019-7.

Abstract

The objective of this study was to determine the incidence of aortic transaction in relation to age, and to examine possible reasons for the observed differences. Data from the North Carolina Medical Database over a 7-year period were examined for the total number of motor vehicle accident victims and for the subset with aortic rupture, based on age at presentation. Data were then divided into 10-year intervals and the differences analyzed using chi-square analysis. Differences among various age groups were statistically significant (P = 0.0001). The highest rate was in the 21-30-year-old age group and average incidence for all ages was 0.7%. High incidence of aortic transaction in the 21-30-year-old group may be due to an increase in high-risk behaviors in such persons, to an improved survival compared with other age ranges, or to an inherent susceptibility of the aorta at this stage of life. These data have important implications for the diagnosis and treatment of aortic transaction and should be taken into account when developing practice guidelines for its management.

摘要

本研究的目的是确定主动脉横断与年龄相关的发生率,并探讨观察到的差异的可能原因。基于就诊时的年龄,对北卡罗来纳医学数据库7年期间机动车事故受害者总数及主动脉破裂子集的数据进行了检查。然后将数据按10年间隔进行划分,并使用卡方分析对差异进行分析。各年龄组之间的差异具有统计学意义(P = 0.0001)。发生率最高的是21至30岁年龄组,所有年龄的平均发生率为0.7%。21至30岁组主动脉横断的高发生率可能是由于该人群中高危行为的增加、与其他年龄范围相比生存率的提高,或者是由于生命这个阶段主动脉的内在易感性。这些数据对主动脉横断的诊断和治疗具有重要意义,在制定其管理的实践指南时应予以考虑。

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