Makiguchi N, Ohsaki Y, Fujiuchi S, Yamamoto Y, Takahashi T, Ide H, Akiba Y, Nakano H, Miyokawa N, Kikuchi K
First Department of Medicine, Asahikawa Medical College, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Jun;35(6):660-4.
A 30-year-old woman was admitted to our hospital because of an abnormal mass shadow in the right side of the mediastinum on a a chest X-ray film. The chest X-ray film and computed tomogram revealed a mass approximately 4.8 cm in diameter in the right side of the mediastinum. The mass had invaded the right supraclavicular fossa. Lymph-node biopsy was done. Microscopical examination of an HE-stained specimen of a supraclavicular lymph nodes showed prediferation of large atypical lymphocytes. These atypical lymphocytes were stained immunohistochemically with anti-Ki-1 antibody. No T cell or B cell markers were found on these cells. No other tumors were detected by radiological examination. Therefore, our diagnosis was anaplastic large-cell lymphoma, which is identical to Ki-1 lymphoma of the mediastinum.
一名30岁女性因胸部X线片显示纵隔右侧有异常肿块阴影而入院。胸部X线片和计算机断层扫描显示纵隔右侧有一个直径约4.8厘米的肿块。该肿块已侵犯右侧锁骨上窝。进行了淋巴结活检。对锁骨上淋巴结的苏木精-伊红染色标本进行显微镜检查，显示大的非典型淋巴细胞增殖。这些非典型淋巴细胞用抗Ki-1抗体进行免疫组织化学染色。这些细胞上未发现T细胞或B细胞标志物。放射学检查未发现其他肿瘤。因此，我们的诊断是间变性大细胞淋巴瘤，与纵隔Ki-1淋巴瘤相同。
