Matsuzawa K, Hamada K, Tokuyama T, Fu A, Nakaya M, Maeda K, Cho S, Narita N
Division of Internal Medicine, Tenri Hospital, Nara, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1997 Jun;35(6):687-91.
A 45-year-old woman was admitted to Nara Medical University Hospital because of right-sided chest pain. Both a chest X-ray film and a chest CT scan revealed bilateral hilar and mediastinal lymphadenopathy and right pleurisy. She underwent fiberoptic bronchoscopy and mediastinoscopy. Biopsy specimens of the lung and mediastinal lymph nodes showed non-caseous epithelioid cell granulomas. After on ophthalmologic examination, she was given a diagnosis of sarcoidosis with a pleural lesion and uveal involvement. The pleurisy become less severe and the lymph nodes shrank without any treatment. About one year later, she complained of right-sided chest pain again and a chest X-ray film revealed diffuse thickening of the pleural on the right side. Examination of pleural biopsy specimens revealed malignant mesothelioma. We know of no previous report from Japan of malignant pleural mesothelioma in a patient with sarcoidosis.
一名45岁女性因右侧胸痛入住奈良医科大学医院。胸部X光片和胸部CT扫描均显示双侧肺门及纵隔淋巴结肿大和右侧胸膜炎。她接受了纤维支气管镜检查和纵隔镜检查。肺和纵隔淋巴结的活检标本显示为非干酪样上皮样细胞肉芽肿。眼科检查后，她被诊断为结节病伴胸膜病变和葡萄膜受累。未经任何治疗，胸膜炎症状减轻，淋巴结缩小。大约一年后，她再次抱怨右侧胸痛，胸部X光片显示右侧胸膜弥漫性增厚。胸膜活检标本检查显示为恶性间皮瘤。我们未找到日本此前关于结节病患者发生恶性胸膜间皮瘤的报道。
