睾丸酮调节睾丸酮丛毛单胞菌中参与类固醇和芳烃分解代谢的酶的表达。
Testosterone-regulated expression of enzymes involved in steroid and aromatic hydrocarbon catabolism in Comamonas testosteroni.
作者信息
Möbus E, Jahn M, Schmid R, Jahn D, Maser E
机构信息
Department of Pharmacology and Toxicology, Philipps University, Marburg, Germany.
出版信息
J Bacteriol. 1997 Sep;179(18):5951-5. doi: 10.1128/jb.179.18.5951-5955.1997.
Abstract
The effect of testosterone as the sole carbon source on protein expression was analyzed in Comamonas testosteroni. Testosterone simultaneously induced the expression of steroid- and aromatic hydrocarbon-catabolizing enzymes and repressed one amino acid-degrading enzyme. It is suggested that steroids play a regulative role in catabolic enzyme synthesis during adaptive growth of C. testosteroni.
摘要
在睾丸酮丛毛单胞菌中分析了以睾酮作为唯一碳源对蛋白质表达的影响。睾酮同时诱导了甾体和芳香烃分解代谢酶的表达，并抑制了一种氨基酸降解酶的表达。这表明甾体在睾丸酮丛毛单胞菌适应性生长过程中的分解代谢酶合成中发挥调节作用。
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