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血管紧张素转换酶抑制剂在心力衰竭治疗中的应用与剂量。医师专业和患者特征的影响。

Utilization and dosing of angiotensin-converting enzyme inhibitors for heart failure. Effect of physician specialty and patient characteristics.

作者信息

Chin M H, Wang J C, Zhang J X, Lang R M

机构信息

Department of Medicine, University of Chicago Medical Center, Ill 60637, USA.

出版信息

J Gen Intern Med. 1997 Sep;12(9):563-6. doi: 10.1046/j.1525-1497.1997.07110.x.

DOI:10.1046/j.1525-1497.1997.07110.x
PMID:9294790
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1497161/
Abstract

To determine if physician specialty is associated with underutilization and underdosing of angiotensin-converting enzyme inhibitors among patients with heart failure, we reviewed the charts of 214 outpatients with decreased systolic function at an urban academic medical center. Regardless of whether patients were cared for by cardiologists, generalist physicians, or a combination of the two specialities, approximately 75% of the patients were taking an angiotensin-converting enzyme inhibitor. However, only approximately 60% of these patients were taking dosages proved to be efficacious in trials. Emphasis on adequate dosing is needed among all specialty groups.

摘要

为了确定医师专业是否与心力衰竭患者中血管紧张素转换酶抑制剂使用不足及剂量不足有关,我们回顾了一家城市学术医疗中心214名收缩功能减退门诊患者的病历。无论患者是由心脏病专家、普通内科医生还是这两个专业的医生联合治疗,约75%的患者正在服用血管紧张素转换酶抑制剂。然而,这些患者中只有约60%服用的剂量在试验中被证明是有效的。所有专业组都需要重视给予足够的剂量。