Engelmann M G, von Smekal A, Knez A, Kürzinger E, Huehns T Y, Höfling B, Reiser M
Medical Department I and Institute for Diagnostic Radiology, Ludwig-Maximilians University, Klinikum Grosshadern, Munich, Germany.
Am J Cardiol. 1997 Sep 1;80(5):569-74. doi: 10.1016/s0002-9149(97)00423-2.
Late outcome after coronary artery bypass grafting (CABG) mainly depends on the status of graft patency. The recent generation of spiral computed tomography (SCT) scanners may have potential in the long-term follow-up of CABG. In this study, graft patency in patients with internal mammary (IMA) and venous CABG was investigated using SCT and angiography. Forty-nine consecutive patients (age 61 +/- 8 years, 45 men) who had undergone CABG were examined by SCT and angiography 22 +/- 6 months after CABG. In total, 134 bypass grafts (42 IMA and 92 venous grafts) were analyzed. The angiographically determined patency rate of grafts was 86% for IMA (n = 36 of 42) and 74% for venous grafts (n = 68 of 92). By SCT, 32 IMA and 64 venous grafts were diagnosed correctly as patent. Sensitivity was 89% (IMA) and 94% (venous); overall sensitivity was 92%. None of the truly occluded venous grafts was diagnosed falsely patent by SCT (specificity 100%), whereas the specificity of IMA graft visualization was somewhat lower (88%, p = NS [overall 97%]). The accuracy for a patent graft was 88% (IMA) and 96% (venous CABG, p = NS). Compared with previous studies, these data suggest that SCT using one of the recent generation scanners (single scan time 0.75 second) is a highly accurate and relatively noninvasive approach for assessing not only saphenous vein graft patency, but also IMA graft patency. To date, this technique has only limited use in visualizing graft stenosis or distal anastomosis site patency.
冠状动脉旁路移植术(CABG)后的远期预后主要取决于移植血管的通畅情况。新一代螺旋计算机断层扫描(SCT)扫描仪在CABG的长期随访中可能具有潜力。在本研究中,使用SCT和血管造影术对接受胸廓内动脉(IMA)和静脉CABG的患者的移植血管通畅情况进行了调查。49例连续接受CABG的患者(年龄61±8岁,45例男性)在CABG术后22±6个月接受了SCT和血管造影检查。总共分析了134条旁路移植血管(42条IMA血管和92条静脉血管)。血管造影确定的IMA血管移植通畅率为86%(42条中的36条),静脉血管移植通畅率为74%(92条中的68条)。通过SCT,32条IMA血管和64条静脉血管被正确诊断为通畅。敏感性分别为89%(IMA血管)和94%(静脉血管);总体敏感性为92%。SCT未将任何真正闭塞的静脉血管误诊为通畅(特异性100%),而IMA血管可视化的特异性略低(88%,p=无显著性差异[总体为97%])。对于通畅移植血管的准确率分别为88%(IMA血管)和96%(静脉CABG,p=无显著性差异)。与先前的研究相比,这些数据表明,使用新一代扫描仪之一(单次扫描时间0.75秒)的SCT不仅是评估大隐静脉移植血管通畅情况,也是评估IMA血管通畅情况的一种高度准确且相对无创的方法。迄今为止,该技术在可视化移植血管狭窄或远端吻合口通畅情况方面的应用有限。