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A profile of the gastrointestinal toxicity of aspirin, indomethacin, oxaprozin, phenylbutazone, and fentiazac in arthritic and Lewis normal rats.

作者信息

Shriver D A, Dove P A, White C B, Sandor A, Rosenthale M E

出版信息

Toxicol Appl Pharmacol. 1977 Oct;42(1):75-83. doi: 10.1016/0041-008x(77)90198-3.

DOI:10.1016/0041-008x(77)90198-3
PMID:929608
Abstract
摘要

相似文献

1
A profile of the gastrointestinal toxicity of aspirin, indomethacin, oxaprozin, phenylbutazone, and fentiazac in arthritic and Lewis normal rats.阿司匹林、吲哚美辛、奥沙普秦、保泰松和芬替扎ac在关节炎大鼠和Lewis正常大鼠中的胃肠道毒性概况。
Toxicol Appl Pharmacol. 1977 Oct;42(1):75-83. doi: 10.1016/0041-008x(77)90198-3.
2
Adverse reactions to non-steroidal antirheumatic drugs.非甾体类抗风湿药物的不良反应。
Curr Med Res Opin. 1974;2(9):600-10. doi: 10.1185/03007997409115265.
3
Local buccal mucosal effects of aspirin, indomethacin and isoxepac: their relationship to gastrointestinal damage.阿司匹林、吲哚美辛和异恶草酮对颊部黏膜的局部作用：它们与胃肠道损伤的关系。
Br J Clin Pharmacol. 1981 May;11(5):528-30. doi: 10.1111/j.1365-2125.1981.tb01165.x.
4
Gastrointestinal bleeding: a possible association with ibuprofen.
Lancet. 1972 May 6;1(7758):1021. doi: 10.1016/s0140-6736(72)91198-1.
5
Gastroscopic evaluation of the effect of aspirin and oxaprozin on the gastric mucosa.阿司匹林和奥沙普秦对胃黏膜影响的胃镜评估。
J Clin Pharmacol. 1981 Apr;21(4):157-61. doi: 10.1002/j.1552-4604.1981.tb05694.x.
6
[Gastro-duodenal tolerance of some drugs with analgesic effect. Clinico-endoscopic considerations].[某些具有镇痛作用药物的胃十二指肠耐受性。临床内镜学考量]
Minerva Med. 1974 Feb 24;65(14):768-77.
7
Endoscopic study of gastro-intestinal injury with non-steroidal anti-inflammatory drugs.
Curr Med Res Opin. 1977;5(1):38-42. doi: 10.1185/03007997709108974.
8
Wy 23205, a new non-steroidal anti-inflammatory agent.Wy 23205，一种新型非甾体抗炎药。
Br J Pharmacol. 1971 Aug;42(4):638P-639P.
9
[Irritative activity of a new anti-inflammatory agent 4-(p-chorophenyl)-2-phenyl-5-thiazoleacetic acid (CH-800) on the gastrointestinal tract in rats (author's transl)].
Nihon Yakurigaku Zasshi. 1979 Nov;75(8):829-36.
10
[The analgesic and antipyretic effects of a non-steroidal anti-inflammatory drug, oxaprozin, in experimental animals].
Nihon Yakurigaku Zasshi. 1984 Apr;83(4):345-54.

引用本文的文献

1
Role of mucus reduction and luminal acid elevation in increased susceptibility of stomach to nonsteroidal antiinflammatory drug-induced injury in arthritic rats.黏液减少和管腔酸升高在关节炎大鼠胃对非甾体抗炎药诱导损伤易感性增加中的作用。
Dig Dis Sci. 2000 Nov;45(11):2175-81. doi: 10.1023/a:1026431623485.
2
An analysis of the gastro-intestinal side-effects of non-steroidal anti-inflammatory drugs, with particular reference to comparative studies in man and laboratory species.非甾体抗炎药胃肠道副作用分析，特别参考人与实验动物的对比研究
Rheumatol Int. 1982;2(1):1-10. doi: 10.1007/BF00541263.
3
Electron microscopic observations comparing the gastric mucosal damage induced in rats and pigs by benoxaprofen and aspirin, reflecting their differing actions as prostaglandin-synthesis-inhibitors.
通过电子显微镜观察比较了贝诺洛芬和阿司匹林对大鼠和猪胃黏膜造成的损伤，这反映了它们作为前列腺素合成抑制剂的不同作用。
Br J Exp Pathol. 1982 Feb;63(1):25-34.
4
Nonsteroidal anti-inflammatory agents: species differences in pharmacodynamics.非甾体抗炎药：药效学中的种属差异
Vet Res Commun. 1983 Dec;7(1-4):359-68. doi: 10.1007/BF02228646.
5
Oxaprozin. A preliminary review of its pharmacodynamic and pharmacokinetic properties, and therapeutic efficacy.奥沙普秦。对其药效学、药代动力学特性及治疗效果的初步综述。
Drugs. 1986 Oct;32(4):291-312. doi: 10.2165/00003495-198632040-00001.
6
Altered susceptibility of arthritic rats to the gastric lesion-inducing effects of aspirin or ethanol and the antilesion effect of rioprostil.关节炎大鼠对阿司匹林或乙醇致胃损伤作用的易感性改变以及利奥前列素的抗损伤作用
Agents Actions. 1987 Oct;22(1-2):134-43. doi: 10.1007/BF01968829.