Ferroir J P, Fénelon G, Billy C, Huon R, Herry J P
Service de Neurologie, Hôpital Tenon, Paris.
Rev Neurol (Paris). 1997 Jun;153(5):354-6.
Epilepsy, frequently with complex partial seizures, is observed in 5.5 p. 100 of all cases of celiac sprue. Bilateral parieto-occipital calcifications in the cortical or subcortical areas are found in about one-half of these patients. This triple association is apparently not fortuitous. Prognosis of epilepsy would depend on how early the gluten-free diet was started. The diagnosis of celiac sprue should be entertained in patients with brain calcifications and epilepsy. Search for anti-endomysium antibodies could provide useful information although villosity atrophy in the proximal portion of the small bowel and its regression with gluten-free diet remain the essential elements for the diagnosis of celiac sprue.
在所有乳糜泻病例中，5.5%的患者患有癫痫，且常伴有复杂部分性发作。在这些患者中，约一半可发现双侧顶枕叶皮质或皮质下区域钙化。这种三联征显然并非偶然。癫痫的预后取决于无麸质饮食开始的时间。对于有脑钙化和癫痫的患者，应考虑乳糜泻的诊断。尽管小肠近端绒毛萎缩及其在无麸质饮食后的恢复仍然是乳糜泻诊断的基本要素，但检测抗肌内膜抗体可能会提供有用信息。
