Dietrich C F, Kirchner J, Higer P, Heyd R, Berkefeld J
Deutsche Klinik für Diagnostik, Wiesbaden.
Aktuelle Radiol. 1997 May;7(3):130-4.
Magnetic resonance imaging (MRI) was performed in 42 patients with proven microadenomas and in 42 patients with normal pituitary hormone analysis. The normal MRI--anatomy of the pituitary gland and its possible variations with measurement of the volume and comparison of the anatomy with that of the gland after changes caused by microadenomas has to our knowledge not yet described. In this study we measured the height, coronary and sagittal diameter of the pituitary gland in both groups as well as other indirect signs of microadenomas (asymmetry of the gland, sella turcica, and the stalk). The pituitary volume indicates the expansion of microadenomas much better than the gland height (and the other diameters). Normal pituitary glands showed a significant lower volume (525 +/- 137 mm3 [R = 225-800 mm3]) than patients with proven microadenomas (734 +/- 393 mm3 [R = 335-2800 mm3], p < 0.001). The normal pituitary gland and sella turcica show a large variety of anatomic variations. These variations are less frequent in healthy subjects (10-21%) than in patients with microadenomas (48-71%). The described criteria are of some value in diagnosis of a suspected gland hypertrophy or microadenoma. In 75% of the patients with normal pituitary parameters and in 12% of the patients with microadenomas no indirect adenoma criteria was found in our study.
对42例经证实患有微腺瘤的患者和42例垂体激素分析正常的患者进行了磁共振成像（MRI）检查。据我们所知，正常垂体的MRI解剖结构及其体积测量以及与微腺瘤引起变化后的腺体解剖结构比较的可能变异尚未见描述。在本研究中，我们测量了两组患者垂体的高度、冠状径和矢状径以及微腺瘤的其他间接征象（腺体、蝶鞍和垂体柄的不对称）。垂体体积比腺体高度（和其他直径）更能显示微腺瘤的扩大情况。正常垂体的体积（525±137mm³[范围=225 - 800mm³]）显著低于经证实患有微腺瘤的患者（734±393mm³[范围=335 - 2800mm³]，p<0.001）。正常垂体和蝶鞍显示出多种解剖变异。这些变异在健康受试者中（10 - 21%）比在微腺瘤患者中（48 - 71%）出现的频率更低。所描述的标准在诊断可疑的腺体肥大或微腺瘤方面具有一定价值。在我们的研究中，75%垂体参数正常的患者和12%微腺瘤患者未发现间接腺瘤标准。
