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[II型糖尿病患者队列中糖尿病视网膜病变的前瞻性研究]

[Prospective studies of diabetic retinopathy in a cohort of patients with type II diabetes mellitus].

作者信息

Luźniak P, Czech A, Tatoń J

机构信息

Katedra i Klinika Chorób Wewnetrznych i Diabetologii Akademii Medycznej w Warszawie.

出版信息

Pol Merkur Lekarski. 1997 Jan;2(7):14-7.

PMID:9296890
Abstract

To gain current data about epidemiology of diabetic retinopathy in a population of type 2 diabetics a long-term prospective study was started. The study included 1334 patients with type 2 diabetes mellitus registered in Warsaw regional Diabetes Center. The prevalence of any form of diabetic retinopathy in this group was 31.4% and proliferative retinopathy-1.3%. It was found that the patients with retinopathy had diabetes mellitus of longer duration, higher fasting and postprandial levels of glycemia and higher daily proteinuria in comparison with diabetics without retinopathy. Apart from that, a frequency of ischemic heart disease and lower extremity ischemic disease was higher in diabetics with retinopathy. 109 new cases of retinopathy were diagnosed during 3-year follow-up. The study allowed us to determine the current epidemiological parameters concerning diabetic retinopathy in type 2 diabetics and a set of parameters characterizing people at highest risk of a development of retinopathy.

摘要

为获取有关2型糖尿病患者人群中糖尿病视网膜病变流行病学的当前数据,开展了一项长期前瞻性研究。该研究纳入了华沙地区糖尿病中心登记的1334例2型糖尿病患者。该组中任何形式糖尿病视网膜病变的患病率为31.4%,增殖性视网膜病变的患病率为1.3%。研究发现,与无视网膜病变的糖尿病患者相比,有视网膜病变的患者糖尿病病程更长,空腹和餐后血糖水平更高,每日蛋白尿更多。除此之外,有视网膜病变的糖尿病患者缺血性心脏病和下肢缺血性疾病的发生率更高。在3年随访期间诊断出109例新的视网膜病变病例。该研究使我们能够确定有关2型糖尿病患者糖尿病视网膜病变的当前流行病学参数,以及一组表征发生视网膜病变风险最高人群的参数。

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