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[细胞辐射失活过程的定量描述。VIII. 真核细胞生殖死亡分析中的微剂量学]

[Quantitative description of the process of radiation inactivation of cells. VIII. Microdosimetry in the analysis of the reproductive death of eukaryotic cells].

作者信息

Barsukov V S

出版信息

Tsitologiia. 1977 Sep;19(9):991-9.

PMID:929699
Abstract

The microdosimetric approach permits to model the first physical stage of radiation damage developing of multistage model of radiation effect. It describes stochastics of absorbed energy distribution among and inside sensitive cell volumes. The analysis of radiobiological effect becoming more complete and adequate. The limits of application of valuable microdosimetric values to characterizing both the quality and quantity of radiation affecting the cells is considered. The aspects of the theory of dual action of radiation well compare with those of the cytogenetic model linking the reproductive cell death with asymmetrical chromosome exchanges.

摘要

微剂量学方法允许对辐射效应多阶段模型中辐射损伤发展的第一个物理阶段进行建模。它描述了敏感细胞体积之间和内部吸收能量分布的随机性。对辐射生物学效应的分析变得更加完整和充分。考虑了有价值的微剂量学值在表征影响细胞的辐射质量和数量方面的应用局限性。辐射双重作用理论的各个方面与将生殖细胞死亡与不对称染色体交换联系起来的细胞遗传学模型的方面进行了很好的比较。

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