Iribarren O
Servicio de Cirugía, Hospital Roy H Glover, Codelco Chile.
Rev Med Chil. 1996 Aug;124(8):999-1005.
Necrotizing soft tissue infection or necrotizing fasciitis is a rapidly progressive inflammation that leads to necrosis of subcutaneous tissues and fascia with secondary necrosis of skin. It is usually attributed to group AB hemolytic streptococci but may be caused by anaerobic bacteria. It occurs with higher frequency in elders, diabetics, alcoholics and patients with impaired immunity. Report mortality rates range from 14 to 80%. An early and timely surgical debridement with remotion of all necrotic tissue is mandatory. Wounds must be closed with splint skin grafts as soon as the local viability of tissues has been assured and the general conditions of the patients allow the procedure. Antibiotics nutritional and hemodynamic support are also necessary.
坏死性软组织感染或坏死性筋膜炎是一种迅速进展的炎症，可导致皮下组织和筋膜坏死，并继发皮肤坏死。它通常由A、B组溶血性链球菌引起，但也可能由厌氧菌引起。在老年人、糖尿病患者、酗酒者和免疫力受损的患者中发病率较高。报告的死亡率在14%至80%之间。早期及时进行手术清创，切除所有坏死组织是必不可少的。一旦确保组织的局部活力且患者的一般状况允许进行该手术，就必须尽快用带蒂皮瓣封闭伤口。抗生素、营养支持和血流动力学支持也是必要的。
