Cabrera Duro A, López Fernández Y, Martínez Corrales P, Rodrigo Carbonero D, Azúa González B, Alcíbar Villa J, Llorente Urcullu A, Rumoroso Cuevas J R, Pastor Menchaca E
Hospital Infantil de Cruces, Baracaldo, Bilbao.
An Esp Pediatr. 1997 Jun;46(6):555-60.
The results of aortic commissurotomy, as the first step in the treatment of aortic valve stenosis in children, have been estimated after a medium-term follow-up.
Twenty-two patients were operated at a mean age of 7.3 +/- 3.6 years of age. Surgery was performed under cardiopulmonary bypass and moderate hypothermia. Twenty patients underwent cardiac catheterization (the systolic gradient pressure was 67.9 +/- 24.7 mmHg and the end diastolic pressure was 17 +/- 7.1 mmHg). We evaluated 10 patients with Doppler flow echocardiography (the valvular area was 0.8 +/- 0.2 cm2/m2). After surgery, we made a follow-up of 8.6 +/- 5.4 years.
The aortic valve was bicuspid in 13 cases and tricuspid in 9 cases. There was no mortality. Before the age of 7, 7 patients developed restenosis. The mean pressure gradient was 92.5 +/- 16.6 mmHg, so six of them underwent valvuloplasty and the other one was operated with an aortic valvulated homograft. The pressure gradient, which was estimated in 20 patients, was lowered to 43.5 +/- 17.5 mmHg and the aortic area was increased to 2.4 cm2/m2. Six patients had a pressure gradient above 40 mmHg. Six patients had previous aortic regurgitation and this reappeared in 3 patients after valvulotomy. At this time, 12 patients have aortic regurgitation, being mild in 9 patients, mild to moderate in 1 and moderate in 2 patients.
Valvulotomy is a palliative therapeutic method. We had no mortality. Restenosis appeared in 7 patients, before the age of seven years, and it can be easily corrected. The aortic regurgitation is usually mild. Valve replacement can be avoided in childhood.
在中期随访后评估了主动脉瓣交界切开术作为儿童主动脉瓣狭窄治疗第一步的效果。
22例患者接受手术,平均年龄7.3±3.6岁。手术在体外循环和中度低温下进行。20例患者接受了心导管检查(收缩期压力阶差为67.9±24.7 mmHg,舒张末期压力为17±7.1 mmHg)。我们用多普勒血流超声心动图评估了10例患者(瓣膜面积为0.8±0.2 cm²/m²)。术后,我们进行了8.6±5.4年的随访。
13例主动脉瓣为二叶式,9例为三叶式。无死亡病例。7岁前,7例患者出现再狭窄。平均压力阶差为92.5±16.6 mmHg,其中6例接受了瓣膜成形术,另1例接受了主动脉瓣膜同种异体移植手术。20例患者评估的压力阶差降至43.5±17.5 mmHg,主动脉瓣面积增加至2.4 cm²/m²。6例患者压力阶差高于40 mmHg。6例患者既往有主动脉瓣反流,瓣膜切开术后3例再次出现反流。此时,12例患者有主动脉瓣反流,9例为轻度,1例为轻度至中度,2例为中度。
瓣膜切开术是一种姑息性治疗方法。我们没有死亡病例。7例患者在7岁前出现再狭窄,且易于纠正。主动脉瓣反流通常为轻度。儿童期可避免瓣膜置换。