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滤泡感染的门诊治疗。

Outpatient treatment of bleb infection.

作者信息

Chen P P, Gedde S J, Budenz D L, Parrish R K

出版信息

Arch Ophthalmol. 1997 Sep;115(9):1124-8. doi: 10.1001/archopht.1997.01100160294005.

Abstract

OBJECTIVE

To determine the outcome of outpatient treatment of bleb infection after trabeculectomy.

DESIGN

Retrospective review.

SETTING

University referral center.

PATIENTS

Twelve eyes with bleb infection and without clinical vitreous involvement of 11 patients treated as out-patients from January 1994 to May 1996.

INTERVENTIONS

After culture of the bleb surface, treatment consisted of intensive topical antibiotics alone (9 eyes), combined with subconjunctival antibiotic injection (1 eye), oral antibiotics (1 eye), or both (1 eye). Five eyes received topical corticosteroids.

MAIN OUTCOME MEASURES

Visual acuity, intraocular pressure, and bleb characteristics.

RESULTS

All eyes responded to treatment within 24 to 48 hours, and recovered visual acuity to within 1 line of the preinfection level. Intraocular pressure continued to be controlled after resolution of infection in 11 eyes (92%); 1 bleb failed and medical therapy was resumed. Bleb leaks were noted during treatment of infection in 11 eyes, and 5 eyes (42%) underwent bleb revision. Organisms cultured from the bleb surface included Staphylococcus aureus (8 eyes), Haemophilus influenzae (2 eyes), and Streptococcus (1 eye). Outpatient treatment costs were estimated to be 78% less than inpatient treatment costs, per 24 hours.

CONCLUSION

Outpatient treatment of bleb infection was efficacious in this group of patients.

摘要

目的

确定小梁切除术后滤过泡感染门诊治疗的效果。

设计

回顾性研究。

地点

大学转诊中心。

患者

1994年1月至1996年5月间11例作为门诊患者接受治疗的患者的12只眼睛,这些眼睛有滤过泡感染且无临床玻璃体受累。

干预措施

在对滤过泡表面进行培养后,治疗包括单独强化局部应用抗生素(9只眼)、联合结膜下注射抗生素(1只眼)、口服抗生素(1只眼)或两者联用(1只眼)。5只眼接受了局部应用糖皮质激素治疗。

主要观察指标

视力、眼压和滤过泡特征。

结果

所有眼睛在24至48小时内对治疗有反应,视力恢复到感染前水平的1行以内。11只眼(92%)感染消退后眼压仍得到控制;1个滤过泡失败,恢复药物治疗。11只眼在感染治疗期间发现滤过泡渗漏,5只眼(42%)进行了滤过泡修复。从滤过泡表面培养出的微生物包括金黄色葡萄球菌(8只眼)、流感嗜血杆菌(2只眼)和链球菌(1只眼)。估计门诊治疗费用比住院治疗费用每24小时低78%。

结论

该组患者滤过泡感染的门诊治疗有效。

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