Kimura H, Itoyama Y, Fujioka S, Ushio Y
Department of Neurosurgery, Kumamoto University Medical School, Japan.
No Shinkei Geka. 1997 Sep;25(9):819-22.
A 65-year-old female with congenital giant, hairy and pigmented nevus developed sudden onset of headache and consciousness disturbance. CT scan revealed a high density mass in the right temporal subcortical region. The high density area suggested hematoma. A right temporal craniotomy was performed. Hemorrhage was observed in a black colored tumor. Histologically, the tumor was malignant melanoma, while the skin tumor was benign intradermal nevi. This patient was diagnosed as neurocutaneous melanosis. Neurocutaneous melanosis belongs to unusual congenital syndrome, and an adult case is very rare. To our knowledge this is the oldest patient to be reported with this disease.
一名65岁女性，患有先天性巨大、多毛且色素沉着的痣，突然出现头痛和意识障碍。CT扫描显示右侧颞叶皮质下区域有一个高密度肿块。高密度区域提示为血肿。遂进行了右侧颞部开颅手术。在一个黑色肿瘤中观察到出血。组织学检查显示，该肿瘤为恶性黑色素瘤，而皮肤肿瘤为良性皮内痣。该患者被诊断为神经皮肤黑素沉着症。神经皮肤黑素沉着症属于罕见的先天性综合征，成年病例非常罕见。据我们所知，这是报道的患此病年龄最大的患者。
