Weitzul S, Duvic M
Department of Dermatology, University of Texas Southwestern Medical Center, Dallas, USA.
Semin Cutan Med Surg. 1997 Sep;16(3):213-8. doi: 10.1016/s1085-5629(97)80044-2.
Infection with the human immunodeficiency virus (HIV) is associated with the development of psoriasis and related disorders, including psoriatic arthritis, dactylitis and enthesitis, and Reiter's syndrome. The etiologic mechanisms remain unclear but most likely represent a combination of genetic and environmental factors. Therapy for these diseases in the setting of HIV infection is often difficult not only because of their characteristically increased severity, but also because the use of conventionally effective immunosuppressive agents may be counterproductive in this patient population.
感染人类免疫缺陷病毒（HIV）与银屑病及相关疾病的发生有关，这些疾病包括银屑病关节炎、指（趾）炎和附着点炎，以及赖特综合征。其病因机制尚不清楚，但很可能是遗传和环境因素共同作用的结果。在HIV感染情况下，治疗这些疾病往往很困难，这不仅是因为它们的严重程度通常会增加，还因为使用传统上有效的免疫抑制剂在这类患者群体中可能会产生适得其反的效果。
