Uzal F A, Glastonbury J R, Kelly W R, Thomas R
Department of Veterinary Pathology, University of Queensland, Brisbane, Australia.
Vet Rec. 1997 Aug 30;141(9):224-6. doi: 10.1136/vr.141.9.224.
Cerebral microangiopathy is described in naturally occurring clostridial enterotoxaemia in two goats. The two cases were selected from the files of two diagnostic laboratories in Australia, on the basis that the clinical syndrome and history were consistent with a diagnosis of enterotoxaemia, and that the diagnosis was confirmed by the identification of epsilon toxin in the intestinal contents. The lesions consisted of acute perivascular proteinaceous exudate in the brain and bilaterally symmetrical foci of encephalomalacia were observed in one of the goats. These brain lesions confirm that Clostridium perfringens type D enterotoxaemia may produce histologically detectable brain changes in goats.
在两只山羊的自然发生的梭菌性肠毒血症中发现了脑微血管病。这两个病例是从澳大利亚两个诊断实验室的档案中挑选出来的，其依据是临床综合征和病史与肠毒血症的诊断相符，并且通过在肠道内容物中鉴定出ε毒素来确诊。病变包括大脑中急性血管周围蛋白质渗出物，并且在其中一只山羊中观察到双侧对称性脑软化灶。这些脑部病变证实，D型产气荚膜梭菌肠毒血症可能在山羊中产生组织学上可检测到的脑部变化。
