Tobias K M, Besser T E
Department of Veterinary Clinical Sciences, College of Veterinary Medicine, Washington State University, Pullman 99164-6610, USA.
J Am Vet Med Assoc. 1997 Sep 15;211(6):715-8.
To assess the relationship of WBC counts and partial oxygen tension in the portal vein and caudal vena cava with portal bacteremia, bacteria in the liver, and postoperative morbidity and mortality in dogs with portosystemic shunts.
Prospective study.
12 clinically normal dogs and 15 dogs with single congenital portosystemic shunts.
Blood was collected from the portal vein and caudal vena cava for aerobic and anaerobic bacterial culture, WBC count, and measurement of partial oxygen tension. Samples of liver tissue, indwelling catheters, and fluids administered IV were also obtained for bacterial culture.
Bacteria were cultured from samples obtained from the portal vein and caudal vena cava of 1 dog with a shunt and from the caudal vena cava of 1 clinically normal dog; neither dog had postoperative complications. In dogs with shunts and in clinically normal dogs, partial oxygen tension in the portal vein was significantly greater than that in the caudal vena cava. Postoperative complications were identified in 33% of dogs with shunts. Partial oxygen tensions of dogs with shunts with postoperative complications did not significantly differ from those of all dogs with shunts or dogs with shunts without complications. Significant differences in WBC counts were not found when comparing dogs with shunts with and without complications. Anaerobic bacteria were not cultured from the liver of any dog.
Leukocytosis, portal bacteremia, and portal hypoxemia were not notable findings in dogs with shunts and were not correlated with postoperative morbidity or mortality.
评估患有门体分流的犬只门静脉和尾腔静脉中白细胞计数及部分氧分压与门静脉菌血症、肝脏细菌感染以及术后发病率和死亡率之间的关系。
前瞻性研究。
12只临床正常犬和15只患有单一先天性门体分流的犬。
从门静脉和尾腔静脉采集血液用于需氧和厌氧细菌培养、白细胞计数以及部分氧分压测量。还获取肝脏组织、留置导管和静脉输注液体的样本用于细菌培养。
从1只患有分流的犬的门静脉和尾腔静脉样本以及1只临床正常犬的尾腔静脉样本中培养出细菌；两只犬均无术后并发症。在患有分流的犬和临床正常犬中，门静脉中的部分氧分压显著高于尾腔静脉。33%患有分流的犬出现术后并发症。出现术后并发症的患有分流的犬的部分氧分压与所有患有分流的犬或无并发症的患有分流的犬的部分氧分压无显著差异。比较有并发症和无并发症的患有分流的犬时，白细胞计数未发现显著差异。任何犬的肝脏均未培养出厌氧菌。
白细胞增多、门静脉菌血症和门静脉低氧血症在患有分流的犬中并非显著发现，且与术后发病率或死亡率无关。
