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用多价梭菌菌苗-类毒素进行加强免疫对育肥牛猝死综合征死亡率的影响。

Effect of booster vaccination with a multivalent clostridial bacterin-toxoid on sudden death syndrome mortality rate among feedlot cattle.

作者信息

De Groot B, Dewey C E, Griffin D D, Perino L J, Moxley R A, Hahn G L

机构信息

Department of Veterinary and Biomedical Sciences, Great Plains Veterinary Educational Center, University of Nebraska-Lincoln, Clay Center 68933, USA.

出版信息

J Am Vet Med Assoc. 1997 Sep 15;211(6):749-53.

PMID:9301747
Abstract

OBJECTIVE

To determine whether booster vaccination with a multivalent clostridial bacterin-toxoid would affect the sudden death syndrome (SDS) mortality rate among feedlot cattle.

DESIGN

Field trial.

ANIMALS

83, 115 cattle at a Nebraska feedlot.

PROCEDURE

Cattle arriving at the feedlot underwent routine processing according to established protocol. All cattle received a sequentially numbered ear tag and a 2-ml dose of a multivalent bacterin-toxoid designed to protect cattle against Clostridium chauvoei, C speticum, C novyi, C sordellii, and C perfringens types C and D. Approximately 90 days prior to slaughter, growth promotants were implanted in all cattle, and cattle were allocated to a treatment or control group on the basis of the last digits of their ear tag numbers. Cattle in the treatment group received a second 2-ml dose of clostridial bacterintoxoid; control cattle did not.

RESULTS

Significant differences between groups in regard to crude, feeding pen, or SDS mortality rates were not detected. Sudden death syndrome mortality rate across both groups was 0.24%. If the SDS mortality rate in midwestern feedlot cattle was reduced > or = 40% by booster vaccination with a multivalent clostridial bacterin-toxoid, this experiment included enough animals to have a 90% probability of detecting that difference.

CLINICAL IMPLICATIONS

Booster vaccination with a multivalent clostridial bacterin-toxoid does not affect SDS mortality rate among feedlot cattle.

摘要

目的

确定用多价梭菌菌苗 - 类毒素进行加强免疫是否会影响饲养场肉牛的猝死综合征(SDS)死亡率。

设计

现场试验。

动物

内布拉斯加州一个饲养场的83115头肉牛。

程序

运抵饲养场的肉牛按照既定方案进行常规处理。所有肉牛都佩戴了顺序编号的耳标,并接种了2毫升多价菌苗 - 类毒素,该菌苗旨在保护肉牛抵御产气荚膜梭菌、腐败梭菌、诺维氏梭菌、索氏梭菌以及C型和D型产气荚膜梭菌。在屠宰前约90天,给所有肉牛植入生长促进剂,并根据耳标号码的最后一位数字将肉牛分配到治疗组或对照组。治疗组的肉牛接受了第二剂2毫升的梭菌菌苗 - 类毒素;对照组的肉牛未接受。

结果

未检测到两组在粗死亡率、饲养栏死亡率或SDS死亡率方面存在显著差异。两组的猝死综合征死亡率均为0.24%。如果用多价梭菌菌苗 - 类毒素进行加强免疫能使中西部饲养场肉牛的SDS死亡率降低≥40%,那么本试验纳入的动物数量足以有90%的概率检测到这种差异。

临床意义

用多价梭菌菌苗 - 类毒素进行加强免疫不会影响饲养场肉牛的SDS死亡率。

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