Burchardt U, Miesel B
Z Gesamte Inn Med. 1977 Jul 1;32(13):319-22.
In 200 healthy test persons of either sex between 15 and 94 years the excretion of the alanine aminopeptidase (EC 3.4.11.2) and of creatinine with the urine was tested. Female test persons excrete smaller quantities of enzymes with the urine than male ones. In the two sexes the efflux of the alanine aminopeptidase only slightly increases with growing age. With regard of the enzyme activities to the creatinine in the urine the curve of excretion is clearly deformed, since in the senium significantly smaller quantities of creatinine are excreted. When an enzyme/creatinine quotient is used reference values specific to age must be used.
对200名年龄在15至94岁之间的健康男女受试者进行了尿液中丙氨酸氨基肽酶(EC 3.4.11.2)和肌酐排泄量的检测。女性受试者尿液中酶的排泄量低于男性。在两性中,丙氨酸氨基肽酶的排泄量仅随年龄增长略有增加。就尿液中酶活性与肌酐的关系而言,排泄曲线明显变形,因为老年期肌酐的排泄量显著减少。当使用酶/肌酐商时,必须使用特定年龄的参考值。