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埃塞俄比亚和瑞典的1型人类免疫缺陷病毒感染患者对p24抗原的体液反应差异可能表明受到类似辅助性T细胞2表型的影响。

Differences in humoral responses to the p24 antigen between Ethiopian and Swedish human immunodeficiency virus type 1-infected patients may suggest influences from a T-helper 2-like phenotype.

作者信息

Kebede T, Britton S, Fehniger T, Vahlne A, Sällberg M

机构信息

Department of Immunology, Microbiology, Pathology, and Infectious Diseases, Karolinska Institutet, Huddinge Hospital, Sweden.

出版信息

Clin Diagn Lab Immunol. 1997 Sep;4(5):627-9. doi: 10.1128/cdli.4.5.627-629.1997.

Abstract

The levels of human immunodeficiency virus type 1 p24 antibodies and p24 antigen among 256 Ethiopians and Africans and 86 Swedes were compared. The elevated levels of total anti-p24 immunoglobulin G (IgG) and anti-p24 IgG4 among the Ethiopian and African patients suggest influences from T-helper-cell type 2-like responses.

摘要

比较了256名埃塞俄比亚人和非洲人与86名瑞典人的1型人类免疫缺陷病毒p24抗体和p24抗原水平。埃塞俄比亚和非洲患者中总抗p24免疫球蛋白G(IgG)和抗p24 IgG4水平升高,提示受到2型辅助性T细胞样反应的影响。

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