Roth M
Z Orthop Ihre Grenzgeb. 1977 Oct;115(5):758-64.
Congenital dislocation of the hip may be readily explained as the result of the osteo-neural growth-in-length disproportion. The theoretical concept is supported by experimental findings in frog tadpoles with "congenital" dislocation of the knee joint produced by osteolathyrogenic diet. In cleared specimens with selective staining of the nervous trunks according to Williams (1943) a growth inhibition of the sciatic nerve responsible for the proximal shift (dislocation) of the tibia may be noted. The tibia is adapted to the growth peculiarities of the sciatic nerve in an essentially similar way like the bony neurocranial capsule to the growing brain. The suggested pathogenetic mechanism appears to apply even to the congenital dislocation of the hip in man.
先天性髋关节脱位可以很容易地解释为骨神经长度生长不均衡的结果。这一理论概念得到了实验结果的支持，在给青蛙蝌蚪喂食致骨软化饮食而产生“先天性”膝关节脱位的实验中，根据威廉姆斯（1943年）的方法对神经干进行选择性染色的透明标本中，可以观察到坐骨神经生长受抑制，这导致了胫骨近端移位（脱位）。胫骨适应坐骨神经生长特性的方式，与骨性神经颅囊适应生长中的大脑的方式基本相似。所提出的发病机制似乎也适用于人类的先天性髋关节脱位。
