Matsushita M, Gao X
Department of Anatomy, Institute of Basic Medical Sciences, University of Tsukuba, Ibaraki, Japan.
J Comp Neurol. 1997 Sep 29;386(3):409-21. doi: 10.1002/(sici)1096-9861(19970929)386:3<409::aid-cne6>3.0.co;2-5.
The dorsal spinocerebellar tract (DSCT) of the thoracic cord (the thoracic DSCT) consists of uncrossed ascending axons originating from Clarke's column, marginal neurons of Clarke's column, and lamina V neurons, and crossed ascending axons originating from neurons in lamina VIII and the ventromedial part of lamina VII. The present study has examined, by using anterograde labeling with biotinylated dextran, whether the thoracic DSCT projects to the cerebellar nuclei. The tracer was injected into the thoracic cord, for two to four segments at levels between the T4 and T9 segments in the rat. The distribution of anterogradely labeled axons and terminals was bilateral but predominantly ipsilateral to the injections. Labeled axons entered the medial nucleus from its rostromedial aspect and terminated widely in medial and ventral parts of the middle subdivision. Furthermore, they terminated in the medial and ventral part of the caudomedial subdivision. Labeled terminals were seen in rostromedial parts of the anterior interpositus nucleus and in medial to caudal parts of the posterior interpositus nucleus. A small number of labeled terminals were consistently seen in the ventral part of the lateral nucleus and the dorsolateral hump region. The present study shows that the thoracic DSCT projects bilaterally, but predominantly ipsilaterally, to the medial and the anterior and posterior interpositus nuclei and suggests that it conveys input related to posture and movement of the trunk and respiratory movement of the thorax.
胸段脊髓的背侧脊髓小脑束（DSCT）（胸段DSCT）由源自克拉克柱、克拉克柱边缘神经元和V层神经元的未交叉上升轴突，以及源自VIII层和VII层腹内侧部神经元的交叉上升轴突组成。本研究通过使用生物素化葡聚糖进行顺行标记，检测胸段DSCT是否投射至小脑核。将示踪剂注入大鼠T4至T9节段之间的胸段脊髓，共两至四个节段。顺行标记的轴突和终末的分布是双侧性的，但主要位于注射部位的同侧。标记的轴突从内侧核的吻内侧进入，并广泛终止于中间亚核的内侧和腹侧部分。此外，它们还终止于尾内侧亚核的内侧和腹侧部分。在前置核的吻内侧部分以及后位核的内侧至尾侧部分可见标记的终末。在外侧核的腹侧部分和背外侧隆起区域始终可见少量标记的终末。本研究表明，胸段DSCT双侧投射，但主要是同侧投射至内侧核以及前位和后位中间核，并提示它传递与躯干姿势和运动以及胸部呼吸运动相关的输入信息。
