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[宽颈颅内动脉瘤治疗中的重建技术。长期血管造影和临床结果。附56例报告]

[Reconstruction technic in the treatment of wide-neck intracranial aneurysms. Long-term angiographic and clinical results. Apropos of 56 cases].

作者信息

Moret J, Cognard C, Weill A, Castaings L, Rey A

机构信息

Fondation Ophtalmologique Rothschild, Département de Neuroradiologie Interventionnelle, Paris.

出版信息

J Neuroradiol. 1997 Jun;24(1):30-44.

PMID:9303942
Abstract

PURPOSE

The main factor limiting endovascular treatment of intracranial aneurysms is the shape of the aneurysmal sac, particularly the width of the neck. In this study we present a new technique to occlude wide neck aneurysms that involves the temporary inflation of a non-detachable balloon in front of the aneurysm neck during each coil placement. The aim of the study is to present the feasibility, efficacy and safety of this "remodeling technique" (RT) as compared to that of "normal" GDC treatment.

MATERIAL AND METHOD

56 aneurysms in 54 patients were selected for treatment with the RT. Thirty-seven (70%) of the patients presented with subarachnoid hemorrhage. Twenty-five (45%) of the aneurysms were located at the vertebrobasilar artery, 24 (43%) at the internal carotid artery, and seven at the level of smaller arteries.

RESULTS

Treatment was achieved in 52 aneurysms in 50 patients. Two aneurysms which were initially not completely occluded underwent a second treatment using the RT. Final results (i.e. the last follow-up angiography or results at the end of the treatment for the cases that have not yet had follow-up) consisted of total occlusion in 40 cases (77%), sub-total occlusion in nine cases (17%), and incomplete occlusion in three cases (6%). Angiographic evidence of clotting was observed during the procedure in three cases, resulting in one permanent deficit (quadranopia). Rupture of the aneurysmal sac occurred during the procedure in three cases, all of which were asymptomatic in the follow-up. Thus, morbidity due to the technique was 1/52 (0.5%) and mortality was 0/56 patients.

CONCLUSION

The remodeling technique allowed the treatment of 52 wide neck or badly shaped aneurysms that were not treatable without this technique. The results of occlusion with the RT seem better than those in our series of normal GDC treatment, and complications related to the technique are fewer. This technique thereby extends the spectrum of treatable aneurysms without increasing the risk incurred by treatment.

摘要

目的

限制颅内动脉瘤血管内治疗的主要因素是动脉瘤囊的形状,尤其是颈部宽度。在本研究中,我们提出一种治疗宽颈动脉瘤的新技术,即在每次放置弹簧圈时,在动脉瘤颈部前方临时充入一个不可拆卸的球囊。本研究的目的是比较这种“重塑技术”(RT)与“常规”GDC治疗的可行性、有效性和安全性。

材料与方法

选取54例患者的56个动脉瘤采用RT治疗。37例(70%)患者出现蛛网膜下腔出血。25个(45%)动脉瘤位于椎基底动脉,24个(43%)位于颈内动脉,7个位于较小动脉水平。

结果

50例患者的52个动脉瘤治疗成功。最初未完全闭塞的2个动脉瘤采用RT进行了二次治疗。最终结果(即最后一次随访血管造影或尚未随访的病例治疗结束时的结果)包括40例(77%)完全闭塞,9例(17%)次全闭塞,3例(6%)不完全闭塞。术中3例观察到血栓形成的血管造影证据,导致1例永久性缺损(象限盲)。术中3例动脉瘤囊破裂,随访中均无症状。因此,该技术导致的并发症发生率为1/52(0.5%),死亡率为0/56例患者。

结论

重塑技术使52个宽颈或形状不佳的动脉瘤得到治疗,而没有该技术则无法治疗这些动脉瘤。RT闭塞的结果似乎优于我们系列常规GDC治疗的结果,且与该技术相关的并发症更少。因此,该技术扩展了可治疗动脉瘤的范围,而不增加治疗带来的风险。

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