Suppr超能文献

[哺乳动物个体发育中的X染色体失活]

[X-chromosome inactivation in mammalian ontogeny].

作者信息

Evdokimova V N, Nazarenko S A

出版信息

Ontogenez. 1997 Jul-Aug;28(4):245-61.

PMID:9304089
Abstract

This review is dedicated to a very interesting problem of developmental genetics: dose compensation of the X-chromosome genes in somatic cells of female mammals. A sequence of events related to X-chromosome inactivation during cell differentiation at the early embryonic stages, association of distributed X-chromosome heterochromatization with developmental pathologies, evolutionary origin of X-inactivation, and its relationship with genomic imprinting are considered.

摘要

本综述致力于发育遗传学中一个非常有趣的问题

雌性哺乳动物体细胞中X染色体基因的剂量补偿。文中考虑了早期胚胎阶段细胞分化过程中与X染色体失活相关的一系列事件、分散的X染色体异染色质化与发育病理学的关联、X染色体失活的进化起源及其与基因组印记的关系。

相似文献

1
[X-chromosome inactivation in mammalian ontogeny].
Ontogenez. 1997 Jul-Aug;28(4):245-61.
2
Dosage compensation in mammals: fine-tuning the expression of the X chromosome.
Genes Dev. 2006 Jul 15;20(14):1848-67. doi: 10.1101/gad.1422906.
3
[X chromosome inactivation in mammals].
Genetika. 1994 Mar;30(3):293-317.
4
Dosage compensation of the active X chromosome in mammals.
Nat Genet. 2006 Jan;38(1):47-53. doi: 10.1038/ng1705. Epub 2005 Dec 11.
5
Co-evolution of X-chromosome inactivation and imprinting in mammals.
Nat Rev Genet. 2005 May;6(5):403-10. doi: 10.1038/nrg1602.
6
Epigenetic dynamics of imprinted X inactivation during early mouse development.
Science. 2004 Jan 30;303(5658):644-9. doi: 10.1126/science.1092727. Epub 2003 Dec 11.
7
Mammalian X-chromosome inactivation: an epigenetics paradigm.
Cold Spring Harb Symp Quant Biol. 2004;69:89-102. doi: 10.1101/sqb.2004.69.89.
8
Developmental aspects of X chromosome inactivation in eutherian and metatherian mammals.
J Exp Zool. 1983 Nov;228(2):271-86. doi: 10.1002/jez.1402280211.
9
[Control of X chromosome inactivation in mammals].
Tanpakushitsu Kakusan Koso. 1999 Sep;44(12 Suppl):1682-90.
10
Genetic conflict and evolution of mammalian X-chromosome inactivation.
Dev Genet. 1995;17(3):206-11. doi: 10.1002/dvg.1020170305.

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验