Kuncz A, Mencser Z, Vörös E, Bodosi M
Idegsebészeti Klinika, Szent-Györgyi Albert Orvostudományi Egyetem, Szeged.
Orv Hetil. 1997 Aug 17;138(33):2051-5.
The experience with a series of 28 posterior fossa exploration and microvascular decompression for trigeminal neuralgia is presented. All the patients were treated with carbamazepine previously and some of them were operated on by destructive methods. The diagnostic work-up consisted of an accurate history, CT or MRI in all cases, and recently (in 17 cases) the vascular compression of the trigeminal nerve was demonstrated directly by MR angiography in the plane of the trigeminal nerve. Microvascular decompression was performed through a suboccipital retromastoid craniotomy. At the operations 21 arterial, 4 venous, 2 combined (arterial + venous) and 1 arachnoid band compression were found. The mean follow up was 30 months. Immediate pain relief was achieved in all cases but one, and there were two recurrences 6 and 12 months later (both of them were venous compression), which have been controllable medically since then. There were 3 permanent hypaesthesia of the face (one of them loss of corneal reflex), 2 hypacusis, 1 cerebrospinal fluid leakage and 1 cerebellar edema as complications. Microvascular decompression is a safe and effective treatment for trigeminal neuralgia and advised if the medical treatment is failed, the patient suitable for general anaesthesia, and there is the evidence of vascular compression of trigeminal nerve on MR angiography.
本文介绍了对28例三叉神经痛患者进行后颅窝探查和微血管减压术的经验。所有患者此前均接受过卡马西平治疗,部分患者曾接受过破坏性手术。诊断性检查包括详细的病史、所有病例均进行CT或MRI检查,最近(17例)通过三叉神经平面的磁共振血管造影直接显示三叉神经的血管压迫。微血管减压术通过枕下乳突后开颅进行。手术中发现21例为动脉压迫、4例为静脉压迫、2例为动静脉联合压迫(动脉+静脉)和1例为蛛网膜带压迫。平均随访30个月。除1例患者外,所有患者术后立即疼痛缓解,术后6个月和12个月有2例复发(均为静脉压迫),此后通过药物治疗可控制。并发症包括3例永久性面部感觉减退(其中1例角膜反射消失)、2例听力减退、1例脑脊液漏和1例小脑水肿。微血管减压术是治疗三叉神经痛的一种安全有效的方法,若药物治疗失败、患者适合全身麻醉且磁共振血管造影有三叉神经血管压迫的证据,则建议采用该方法。