[人对氧磷酶的多态性及临床意义]
[Polymorphism and clinical significance of human paraoxonase enzyme].
作者信息
Renczes G, Róna K, Szabó I, Somogyi A
机构信息
Haynal Imre Egészségtudományi Egyetem, I. Belgyógyászati Klinika, Budapest.
出版信息
Orv Hetil. 1997 Aug 17;138(33):2057-9.
PMID:9304097
Abstract
The human serum paraoxonase (PON) in one of the enzymes showing pharmacogenetic polymorphism. According to our present knowledge the enzyme inhibits the lipidperoxydation and through its effect on the lipid metabolism or another pathogenetic mechanism may take part in the pathogenesis of diabetes mellitus and ishaemic heart disease.
摘要
人血清对氧磷酶（PON）是表现出药物遗传多态性的酶之一。根据我们目前的认知，该酶可抑制脂质过氧化，并且通过其对脂质代谢的影响或其他致病机制，可能参与糖尿病和缺血性心脏病的发病过程。
Zotero 插件