Krasnianskiĭ V P, Gradoboev V N, Borisevich I V, Potryvaeva N V, Lebedinskaia E V, Chernikova N K, Timan'kova G D
Vopr Virusol. 1997 Jul-Aug;42(4):168-71.
A horse may serve the producer of immune antiserum to Lassa virus. Specific immunoglobulin with at least 1:512 titer of virus-neutralizing antibodies to Lassa fever was obtained by alcohol sedimentation after Cohn from the blood serum of immunized horses. The preparation does not differ from heterologous commercial immunoglobulins. Preclinical studies of immunoglobulin to Lassa fever demonstrated its safety and a high specific activity. The agent can be injected both alone and in combination with virasole.
马可用于制备抗拉沙病毒免疫抗血清。通过科恩（Cohn）法乙醇沉淀，从免疫马的血清中获得了病毒中和抗体效价至少为1:512的抗拉沙热特异性免疫球蛋白。该制剂与异源商业免疫球蛋白无异。抗拉沙热免疫球蛋白的临床前研究证明了其安全性和高特异性活性。该制剂既可以单独注射，也可以与病毒唑联合注射。
