Dunn D W, Austin J K, Huster G A
Indiana University School of Medicine, Indianapolis, USA.
Seizure. 1997 Aug;6(4):283-7.
Behaviour problems are common in children with epilepsy and it is not known when these problems begin. Some suggest that behaviour problems are caused by a neurological condition that also causes the seizures. Behaviour problems were investigated in 42 youths (23 girls and 19 boys) over a 4-month period beginning at the time of the initial seizure. Subjects were aged 4-15 years (mean, M = 8.4). Approximately 57% had partial seizure(s) and 43% had generalized seizure(s). The large majority (71%) were diagnosed with epilepsy. As a part of a larger study, parents rated their children's behaviour on the Child Behaviour Checklist immediately prior to the first seizure (time 1), and at 4 months after the first seizure (time 2). Seizure severity was rated as follows: high = 20%, moderate = 39%, and low = 41%. At time 1, 24% already had behaviour problems. Behaviour problems significantly decreased from time 1 to time 2 (P < 0.001) for the whole group. Within the epilepsy group (n = 40), differences were found in behaviour problems based on seizure severity from time 1 to time 2 as follows: low, time 1: M = 55, time 2: M = 45; moderate, time 1: M = 55, time 2: M = 51; and high, time 1: M = 61, time 2: M = 55. Results indicate that children should be assessed for behaviour problems at the time of the first seizure.
行为问题在癫痫患儿中很常见，且这些问题何时开始尚不清楚。一些人认为行为问题是由一种也会引发癫痫发作的神经疾病引起的。在42名青少年（23名女孩和19名男孩）中进行了行为问题调查，调查从首次癫痫发作时开始，为期4个月。受试者年龄在4至15岁之间（平均年龄，M = 8.4）。约57%的人有部分性癫痫发作，43%的人有全身性癫痫发作。绝大多数（71%）被诊断为癫痫。作为一项更大规模研究的一部分，家长在首次癫痫发作前（时间1）以及首次癫痫发作后4个月（时间2），根据儿童行为量表对孩子的行为进行评分。癫痫发作严重程度的评级如下：高 = 20%，中 = 39%，低 = 41%。在时间1时，24%的人已经存在行为问题。整个组从时间1到时间2行为问题显著减少（P < 0.001）。在癫痫组（n = 40）中，发现从时间1到时间2，基于癫痫发作严重程度的行为问题存在差异如下：低，时间1：M = 55，时间2：M = 45；中，时间1：M = 55，时间2：M = 51；高，时间1：M = 61，时间2：M = 55。结果表明，在首次癫痫发作时就应对儿童的行为问题进行评估。
