School of Medicine, Aristotle University of Thessaloniki, Greece.
Epilepsy Res. 2012 Jun;100(1-2):104-12. doi: 10.1016/j.eplepsyres.2012.01.014. Epub 2012 Feb 19.
The present study examined whether the perceived behavioral problems of children with idiopathic epilepsy differed from those of healthy controls according to parent proxy-reports and which factors are associated with these problems. The parents of 106 children with idiopathic epilepsy and 305 healthy controls aged 6-9 years old completed the Vanderbilt ADHD Diagnostic Parent Rating Scale and the Strengths and Difficulties Questionnaire. The 106 children with idiopathic epilepsy were also interviewed using the K-SADS-PL. The parents of children with idiopathic epilepsy reported more hyperactivity, emotional and conduct problems than the parents of healthy controls, as well as less prosocial behavior. Parents detected no differences in peer problems, inattention, oppositional/defiant disorder, and anxiety/depression. Age of onset of epilepsy (later), the number of administered antiepileptic drugs (polytherapy), and gender (male) predicted behavioral problems in children with idiopathic epilepsy. The frequency of seizures was associated with behavioral problems, while age was not. Finally, children with benign focal epilepsy were rated by their parents as having less behavioral problems than children with generalized epilepsy.
本研究旨在探讨儿童特发性癫痫的父母报告的感知行为问题是否与健康对照组存在差异，以及哪些因素与这些问题相关。研究纳入了 106 名特发性癫痫患儿和 305 名年龄在 6-9 岁的健康对照组的父母，让他们完成了范德比尔特多动症诊断父母评定量表和长处和困难问卷。对 106 名特发性癫痫患儿还使用 K-SADS-PL 进行了访谈。特发性癫痫患儿的父母报告的多动、情绪和行为问题比健康对照组的父母多，亲社会行为较少。父母在同伴问题、注意力不集中、对立违抗障碍和焦虑/抑郁方面没有发现差异。癫痫发病年龄（较晚）、使用的抗癫痫药物数量（联合治疗）和性别（男性）可预测特发性癫痫患儿的行为问题。癫痫发作频率与行为问题相关，而与年龄无关。最后，父母认为良性局灶性癫痫患儿的行为问题比全身性癫痫患儿少。
