居住在阿拉伯联合酋长国阿布扎比的阿拉伯和巴基斯坦人群中HLA - DQα及多标记物（低密度脂蛋白受体、维生素D结合蛋白、血型糖蛋白A、β - 球蛋白及D7S8）等位基因的分布情况。
Distribution of HLA-DQ alpha and polymarker (LDLR, GC, GYPA, HBGG, and D7S8) alleles in Arab and Pakistani populations living in Abu Dhabi, United Arab Emirates.
作者信息
Tahir M A, Caruso J, Budowle B, Aziz N, Novick G E
机构信息
Indianapolis-Marion County Forensic Services Agency, IN, USA.
出版信息
J Forensic Sci. 1997 Sep;42(5):914-8.
Randomly collected blood samples from 100 Arabs and 100 Pakistanis residing in Abu Dhabi were analyzed using the HLA-DQ alpha and polymarker (LDLR, GC, GYPA, HBGG, D7S8) PCR based reverse dot blot systems. Allelic frequencies for each allele and observed heterozygosity for each locus were calculated. Departures from Hardy-Weinberg expectations (HWE) were determined using the unbiased estimate of the expected homozygote/ heterozygote frequencies, the likelihood ratio test and the exact test. No significant departures from HWE expectations were detected.
使用基于HLA-DQα和多标记物（低密度脂蛋白受体、维生素D结合蛋白、血型糖蛋白A、β-球蛋白、D7S8）聚合酶链反应的反向斑点杂交系统，对随机收集的居住在阿布扎比的100名阿拉伯人和100名巴基斯坦人的血样进行了分析。计算了每个等位基因的等位基因频率以及每个基因座的观察杂合度。使用预期纯合子/杂合子频率的无偏估计、似然比检验和确切检验来确定与哈迪-温伯格平衡预期（HWE）的偏差。未检测到与HWE预期有显著偏差。
Zotero 插件