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[药物溶液用注射器针头和橡胶瓶塞产生的颗粒污染研究]

[Study on particle contamination produced by syringe needles and rubber stoppers for pharmaceutical solutions].

作者信息

Zhao L, Wang H S, Han Z F

机构信息

General Hospital of P. L. A. Beijing.

出版信息

Zhonghua Hu Li Za Zhi. 1997 Jan;32(1):12-4.

PMID:9304949
Abstract

The contamination of particles produced by syringe needles and rubber stoppers for pharmacal solution of venous transfusion was studied. The results showed that the contamination of particles was positive correlation with the usage frequency of syringe needles, so the syringe needles for single use were suggested. To compare two kinds of syringe needles with different structure (side hole and incline), the result was that the difference of particle contamination between them was similar and without statistic significance. The particles contamination produced by primary and used rubber stoppers which was protected by polyester film was studied. It was shown that the difference between them was no significant statistically. The results of this study supplyed a scientific evidence about repeated use of rubber stoppers.

摘要

对静脉输液药物溶液注射器针头和橡胶塞产生的微粒污染进行了研究。结果表明,微粒污染与注射器针头的使用频率呈正相关,因此建议使用一次性注射器针头。为比较两种不同结构(侧孔和斜面)的注射器针头,结果是它们之间的微粒污染差异相似且无统计学意义。对用聚酯薄膜保护的原装和用过的橡胶塞产生的微粒污染进行了研究。结果表明,它们之间的差异无统计学意义。本研究结果为橡胶塞重复使用提供了科学依据。

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