Ding Z H, Liu W K, Ding J Y
Department of Anatomy, Jinan Medical School of PLA.
Zhonghua Hu Li Za Zhi. 1997 Mar;32(3):128-31.
The sciatic nerve of 16 rabbits were examined with the optical and electron microscope 2, 24, 72 hours and 7 days after injecting penicillin (200,000 U) into nerve or its peripheral in experiment group and control group. The experiment group showed successively nerve fiber tumefaction, myelin sheath lamellar separation and degeneration partly, the construction of axonal change abnormality myelin and axonal obvious degeneration from 2 hours to 7 days. The control group showed perinerve edema, hyperemia, epineurium hyperplasia, the nerve fiber of near epineurium had mild pathologic changes.
在实验组和对照组中，于神经或其外周注射青霉素（200,000单位）后2小时、24小时、72小时和7天，用光学显微镜和电子显微镜对16只家兔的坐骨神经进行检查。实验组从2小时到7天依次出现神经纤维肿胀、髓鞘板层分离和部分变性，轴突改变异常，髓鞘和轴突明显变性。对照组表现为神经周围水肿、充血、神经外膜增生，靠近神经外膜的神经纤维有轻度病理改变。
