Burgett R A, Purvin V A, Kawasaki A
Department of Ophthalmology, Indiana University Medical Center, Indianapolis, USA.
Neurology. 1997 Sep;49(3):734-9. doi: 10.1212/wnl.49.3.734.
To clarify the appropriate role of lumboperitoneal (LP) shunting in the surgical management of pseudotumor cerebri (PTC), we retrospectively analyzed the clinical data from 30 patients who underwent this procedure. We found LP shunting to be an effective means of acutely lowering intracranial pressure. Symptoms of increased intracranial pressure improved in 82% of patients. Among 14 eyes with impaired visual acuity, 10 (71%) improved by at least two lines. Worsening of vision occurred in only one eye. Of 28 eyes with abnormal Goldmann perimetry, 18 (64%) improved and none worsened. The incidence of serious complications was low. The major drawback of LP shunting was the need for frequent revisions in a few patients. The reason for poor shunt tolerance in certain individuals is unclear. In PTC, LP shunting should be considered as the first surgical procedure for patients with severe visual loss at presentation or with intractable headache (with or without visual loss). After shunting it is important to identify patients who are shunt intolerant.
为明确腰大池腹腔(LP)分流术在假性脑瘤(PTC)外科治疗中的恰当作用,我们回顾性分析了30例行该手术患者的临床资料。我们发现LP分流术是急性降低颅内压的有效方法。82%的患者颅内压升高症状得到改善。在14只视力受损的眼睛中,10只(71%)至少提高了两行视力。仅1只眼睛视力恶化。在28只Goldmann视野检查异常的眼睛中,18只(64%)得到改善,无恶化情况。严重并发症的发生率较低。LP分流术的主要缺点是少数患者需要频繁进行分流管修订。某些个体对分流耐受性差的原因尚不清楚。在PTC中,对于就诊时严重视力丧失或顽固性头痛(无论有无视力丧失)的患者,应将LP分流术视为首选手术方法。分流术后,识别对分流不耐受的患者很重要。