Complete nucleotide sequence of the HLA-DRB1 *1302 allele.

作者信息

Martinez-Quiles N, Martin-Villa J M, Martinez-Laso J, Ferre-Lopez S, Alvarez M, Gomez-Casado E, de Juan M D, Arnaiz-Villena A

机构信息

Hospital Universitario 12 de Octubre, Universidad Complutense, Madrid, Spain.

出版信息

Eur J Immunogenet. 1997 Aug;24(4):287-90. doi: 10.1111/j.1365-2370.1997.tb00022.x.

DOI:10.1111/j.1365-2370.1997.tb00022.x

PMID:9306097

Abstract

Sequencing studies of HLA class II molecules have focused almost exclusively on its exon 2. The complete cDNA sequence of the DRB*1302 allele is reported here for the first time. A conservative polymorphism was detected outside the exon 2 at residue 206; these changes can only be recorded if complete cDNA sequences are studied, and may be of value in drawing evolutive inferences.

摘要