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A novel DRB1*0801 haplotype carrying DRB3*0202 found in a German pedigree.

作者信息

Chen D F, Pastucha L T, Albert E D, Seibert I, Volgger A, Yao Z, Pein C D, Tillmann H L, Manns M P, Stangel W

机构信息

Blutbank-Immunhämatologie-Transfusionsmedizin, Medizinische Hochschule Hannover, Germany.

出版信息

Eur J Immunogenet. 1997 Dec;24(6):435-7. doi: 10.1046/j.1365-2370.1997.d01-116.x.

DOI:10.1046/j.1365-2370.1997.d01-116.x
PMID:9534042
Abstract

DRB108 haplotypes have not been known to carry a DRB3 gene. We have found a patient suffering from liver disease who has a novel HLA haplotype of DRB10801 with DRB3*0202 as established by family segregation. These two genes were confirmed by sequencing. DR8 and DR52 antigen specificities were serologically detected, indicating expression of these genes.

摘要

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