Petersson I F, Boegård T, Saxne T, Silman A J, Svensson B
Spenshult's Hospital for Rheumatic Diseases, Halmstad, Sweden.
Ann Rheum Dis. 1997 Aug;56(8):493-6. doi: 10.1136/ard.56.8.493.
To determine the prevalence of tibiofemoral radiographic knee osteoarthritis (OA) in people aged 35-54 years associated with chronic (> 3 months) knee pain using two different radiographic grading systems.
Population based postal survey in a random sample of inhabitants in a district in southern Sweden followed by clinical examination and plain posteroanterior, weight bearing radiographical examination. The Ahlbäck criteria (focusing on joint space narrowing) and the Kellgren & Lawrence classification for knee OA were used for diagnosing tibiofemoral OA.
A questionnaire was sent to 2000 randomly selected people aged 35-54 years. The response rate was 92.6%. Fifteen per cent of these people reported chronic knee pain. This group (n = 279) was offered a clinical and radiographic examination of the knee joint and 204 persons agreed to participate. According to the Kellgren & Lawrence classification 28 subjects had OA of the knee grade 2 or more and 16 grade 3 or more. Radiographically detected OA of the knee according to Ahlbäck was found in 20 cases. The minimum prevalence of radiological tibiofemoral knee OA with knee pain was thus 1.5% for Kellgren & Lawrence grade 2 or more, 0.9% for grade 3 or more, and 1.1% according to the Ahlbäck classification. The agreement between the Kellgren & Lawrence grades 2-3 versus Ahlbäck grade I as well as grade 3-4 versus Ahlbäck grade I-II was good (kappa 0.76 and 0.78 respectively).
The prevalence of radiographic tibiofemoral OA combined with chronic knee pain in people aged 35-54 years was around 1% as estimated by either the Kellgren & Lawrence or the Ahlbäck classifications systems. Prospective follow up of this cohort should elucidate the significance of knee pain as a sign of developing OA.
采用两种不同的影像学分级系统,确定35 - 54岁伴有慢性(> 3个月)膝关节疼痛人群中胫股关节影像学膝关节骨关节炎(OA)的患病率。
对瑞典南部一个地区的居民进行随机抽样的基于人群的邮政调查,随后进行临床检查以及负重后前位X线平片检查。使用阿尔贝克标准(侧重于关节间隙变窄)和膝关节OA的凯尔格伦与劳伦斯分类法来诊断胫股关节OA。
向2000名随机选取的35 - 54岁人群发送了问卷。回复率为92.6%。这些人中15%报告有慢性膝关节疼痛。该组(n = 279)接受了膝关节的临床和影像学检查,204人同意参与。根据凯尔格伦与劳伦斯分类法,28名受试者患有2级或更高等级的膝关节OA,16名患有3级或更高等级。根据阿尔贝克标准,影像学检测到20例膝关节OA。因此,伴有膝关节疼痛的胫股关节影像学膝关节OA的最低患病率,凯尔格伦与劳伦斯2级或更高等级为1.5%,3级或更高等级为0.9%,阿尔贝克分类法为1.1%。凯尔格伦与劳伦斯2 - 3级与阿尔贝克I级以及3 - 4级与阿尔贝克I - II级之间的一致性良好(kappa分别为0.76和0.78)。
根据凯尔格伦与劳伦斯或阿尔贝克分类系统估计,35 - 54岁人群中伴有慢性膝关节疼痛的胫股关节影像学OA患病率约为1%。对该队列进行前瞻性随访应能阐明膝关节疼痛作为OA发展迹象的意义。