Quantin X, Pujol J L, Lehmann M, Simony J, Serre I, Michel F B
Chest Department, University Hospital of Montpellier, Arnaud de Villeneuve Hospital, France.
Cancer Detect Prev. 1997;21(5):418-25.
We analyzed the survival of 89 surgically treated patients presenting non-small-cell lung cancer in regard to the accumulation of p53 protein as detected by indirect immunoperoxidase reactivity of PAb1801 anti-human p53 protein. Although the well-known factors such as stage grouping, tumor status, and nodal status were found to be prognostic determinants, the p53 protein accumulation had no effect on either univariate analysis or multivariate analysis of survival.
我们分析了89例接受手术治疗的非小细胞肺癌患者的生存情况，这些患者的p53蛋白积累情况通过抗人p53蛋白的PAb1801间接免疫过氧化物酶反应性检测。尽管发现诸如分期分组、肿瘤状态和淋巴结状态等众所周知的因素是预后决定因素，但p53蛋白积累对生存的单因素分析或多因素分析均无影响。
