Young J B
Department of Cardiology, Cleveland Clinic, USA.
Cleve Clin J Med. 1997 Sep;64(8):415-22. doi: 10.3949/ccjm.64.8.415.
Although beta blockers were once contraindicated in patients with heart failure, a growing understanding of the role of the sympathetic nervous system in heart failure is rekindling interest in these drugs. In particular, the beta blocker carvedilol is a valuable adjunctive treatment for mild-to-moderate compensated congestive heart failure, regardless of etiology. The utility of carvedilol appears to be related to its specific properties.
尽管β受体阻滞剂曾被列为心力衰竭患者的禁忌药物,但对交感神经系统在心力衰竭中作用的认识不断深入,重新燃起了人们对这些药物的兴趣。特别是,β受体阻滞剂卡维地洛是轻至中度代偿性充血性心力衰竭的一种有价值的辅助治疗药物,无论其病因如何。卡维地洛的效用似乎与其特定特性有关。