Singh J, Bora D, Sachdeva V, Sharma R S, Verghese T
National Institute of Communicable Diseases, Delhi, India.
J Diarrhoeal Dis Res. 1997 Mar;15(1):3-6.
In Delhi, patients with cholera-like illness are admitted to the Infectious Diseases Hospital. In 1993, rectal swabs from 836 such patients aged less than five years were examined for the presence of Vibrio cholerae O1 and O139. Of them, 232 (28%), 180 (22%), and 424 (51%) were found suffering from O1 cholera, O139 cholera, and non-cholera watery diarrhoea respectively. Twelve children (1.4%) excreted both V. cholerae O1 and O139. Both types of cholera were similarly distributed by age, with 19% of the cases occurring in infants. The findings indicate that cholera should be suspected in children aged less than two years and in infants with acute watery diarrhoea. For both serotypes, males were more represented than females; the differences were, however, not significant. Clinical features of patients with V. cholerae O139 and O1 were indistinguishable, except that a significantly higher percentage of the former had fever. Potential risk factors for cholera were almost equally prevalent in the families of children aged less than 5 years having either O1 or O139 cholera. The results suggest a similar mode of transmission of the two serotypes in children. By inference, the preventive and control measures are also likely to be similar.
在德里，患有霍乱样疾病的患者被收治到传染病医院。1993年，对836名年龄小于5岁的此类患者进行直肠拭子检查，以检测霍乱弧菌O1和O139的存在情况。其中，分别有232名（28%）、180名（22%）和424名（51%）被发现患有O1型霍乱、O139型霍乱和非霍乱性水样腹泻。12名儿童（1.4%）同时排出霍乱弧菌O1和O139。两种类型的霍乱在年龄分布上相似，19%的病例发生在婴儿中。研究结果表明，对于急性水样腹泻的2岁以下儿童和婴儿应怀疑患有霍乱。对于两种血清型，男性的比例均高于女性；然而，差异并不显著。除了前者发热的比例明显更高外，霍乱弧菌O139和O1患者的临床特征无法区分。年龄小于5岁的患有O1或O139霍乱的儿童家庭中，霍乱的潜在风险因素几乎同样普遍。结果表明，两种血清型在儿童中的传播方式相似。由此推断，预防和控制措施可能也相似。
