Back M R, Harward T R, Huber T S, Carlton L M, Flynn T C, Seeger J M
Section of Vascular Surgery, University of Florida College of Medicine, Gainesville 32610-0286, USA.
J Vasc Surg. 1997 Sep;26(3):456-62; discussion 463-4. doi: 10.1016/s0741-5214(97)70038-7.
Carotid endarterectomy (CEA) has been shown to significantly reduce the risk of stroke caused by carotid artery stenosis. Limiting the costs of CEA without increasing the risks will improve the cost-effectiveness of this procedure.
Results were prospectively collected from 63 consecutive CEAs performed in 60 patients who were entered into a clinical pathway for CEA that included avoidance of cerebral arteriography, preferential use of regional anesthesia, selective use of the intensive care unit (ICU), and early hospital discharge. The mortality rate, complications, hospital costs, and net income in these patients were then compared with results from 45 CEAs performed in 42 consecutive patients immediately before beginning the CEA pathway. Age, comorbid risk factors, incidence of symptoms, and degree of carotid artery stenosis were similar in both patient groups.
The rates of mortality and complications associated with CEA were low (mortality rate, 0%; stroke, 0.9%; transient ischemic attack, 2.8%) and did not vary between the two groups. Implementation of the CEA pathway resulted in significant (p < 0.001) reductions in the use of arteriography (74% to 13%), general anesthesia (100% to 24%), ICU use (98% to 30%), and mean hospital length of stay (5.8 days to 2.0 days). These changes resulted in a 41% reduction in mean total hospital cost ($9652 to $5699) and a 124% increase in mean net hospital income ($1804 to $4039) per CEA (p < 0.01). For the 39 patients (62%) who achieved all elements of the CEA pathway, the mean hospital length of stay was 1.3 days, the mean hospital cost was $4175, and the mean hospital income was $4327.
Costs associated with CEA can be reduced substantially without increased risk. This makes CEA an extremely cost-effective treatment of carotid disease against which new therapeutic approaches must be measured.
颈动脉内膜切除术(CEA)已被证明能显著降低由颈动脉狭窄引起的中风风险。在不增加风险的情况下限制CEA的成本将提高该手术的成本效益。
前瞻性收集了60例患者连续进行的63例CEA的结果,这些患者进入了CEA临床路径,包括避免脑动脉造影、优先使用区域麻醉、选择性使用重症监护病房(ICU)以及早期出院。然后将这些患者的死亡率、并发症、住院费用和净收入与在CEA路径开始前连续42例患者进行的45例CEA的结果进行比较。两组患者的年龄、合并症风险因素、症状发生率和颈动脉狭窄程度相似。
与CEA相关的死亡率和并发症发生率较低(死亡率为0%;中风为0.9%;短暂性脑缺血发作为2.8%),两组之间无差异。CEA路径的实施导致动脉造影的使用(从74%降至13%)、全身麻醉(从100%降至24%)、ICU使用(从98%降至30%)以及平均住院时间(从5.8天降至2.0天)显著减少(p<0.001)。这些变化使平均总住院费用降低了41%(从9652美元降至5699美元),每例CEA的平均住院净收入增加了124%(从1804美元增至4039美元)(p<0.01)。对于实现了CEA路径所有要素的39例患者(62%),平均住院时间为