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[使用体外循环进行全身热疗治疗肺癌]

[Treatment of lung cancer by total-body hyperthermia using an extracorporeal circuit].

作者信息

Maeta M

出版信息

Rinsho Kyobu Geka. 1989 Dec;9(6):540-4.

PMID:9308657
Abstract

Since far-advanced cancer shows extended infiltration into neighboring organs and/or metastasis to other organs, induction of total-body hyperthermia appears to be a reasonable treatment. The method of hyperthermia, which employs an extracorporeal circuit that incorporates a heat exchanger, facilitates the rapid heat induction and provides accurate temperature control. The most favorable antitumor effects were obtained for patients with lung cancer among miscellaneous cancer. Irrespective of whether the tumors were primary or secondary lesions or recurrences, favorable results were obtained in patients whose tumors were in the lung. The complication and mortality increased in proportion to the reduction of the performance status of patients before treatment. These findings indicate that total-body hyperthermia should be used as therapy for patients with primary or metastatic lung cancer and then on patients in generally good condition.

摘要

由于晚期癌症表现为向邻近器官的广泛浸润和/或转移至其他器官,全身热疗似乎是一种合理的治疗方法。热疗方法采用了包含热交换器的体外循环,便于快速诱导发热并提供精确的温度控制。在各种癌症中,肺癌患者获得了最有利的抗肿瘤效果。无论肿瘤是原发性、继发性病变还是复发,肺部有肿瘤的患者都取得了良好的效果。并发症和死亡率随着治疗前患者身体状况的下降而增加。这些发现表明,全身热疗应用于原发性或转移性肺癌患者以及一般状况良好的患者。

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1
[Treatment of lung cancer by total-body hyperthermia using an extracorporeal circuit].[使用体外循环进行全身热疗治疗肺癌]
Rinsho Kyobu Geka. 1989 Dec;9(6):540-4.
2
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Int J Radiat Oncol Biol Phys. 2009 Jan 1;73(1):128-35. doi: 10.1016/j.ijrobp.2008.03.059. Epub 2008 May 29.
9
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