Horoupian D S, Shuster D L, Kaarsoo-Herrick M, Shuer L M
Department of Pathology (Neuropathology), Stanford University, CA 94305, USA.
Hum Pathol. 1997 Sep;28(9):1111-4. doi: 10.1016/s0046-8177(97)90066-6.
We report two cases of central neurocytoma; one located in the right lateral ventricle and associated with a distinctly separate primitive neuroectodermal tumor (PNET)/medulloblastoma of the fourth ventricle, and the other admixed with fat cells and arising from the left lateral and third ventricles with extension into the corpus callosum. We discuss that concurrent occurrences of PNET and adipose tissue are not fortuitous events, but an evidence that neurocytomas and PNETs originate in the residual germinal pool from common progenitor cell rests recapitulating features of developing neurons and with a potential for mesenchymal differentiation.
我们报告了两例中枢神经细胞瘤；一例位于右侧脑室，与第四脑室一个明显独立的原始神经外胚层肿瘤（PNET）/髓母细胞瘤相关，另一例混有脂肪细胞，起源于左侧脑室和第三脑室并延伸至胼胝体。我们讨论了PNET和脂肪组织的同时出现并非偶然事件，而是神经细胞瘤和PNET起源于残留生发池中的共同祖细胞残余的证据，这些祖细胞重现了发育中神经元的特征并具有间充质分化的潜力。
