Hino O
Dept. of Experimental Pathology, Cancer Institute.
Gan To Kagaku Ryoho. 1997 Sep;24(11):1386-91.
Hereditary cancer is rare, but it has served as a useful model in the understanding of carcinogenesis. A number of cancer genes have been identified by the study of hereditary human cancers and implicated in sporadic forms of the some tumors. In this article, I reviewed von Hippel-Lindau disease (VHL) gene and tuberous sclerosis 2 (TSC 2) gene.
遗传性癌症很罕见，但它在理解癌症发生过程中是一个有用的模型。通过对人类遗传性癌症的研究，已经鉴定出许多癌症基因，并发现它们与某些肿瘤的散发性形式有关。在本文中，我回顾了冯·希佩尔-林道病（VHL）基因和结节性硬化症2（TSC 2）基因。
