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[儿童癫痫]

[Epilepsy in childhood].

作者信息

Wenzel D

机构信息

Klinik und Poliklinik für Kinder und Jugendiche, Friedrich-Alexander-Universität Erlangen-Nürnberg.

出版信息

Z Arztl Fortbild Qualitatssich. 1997 Jun;91(3):257-66.

PMID:9312431
Abstract

With a morbidity of 0.8%, epilepsy in childhood is one of the most frequent chronic diseases of the CNS. Improved diagnostic and therapeutical options of the last two decades made it possible that today 60-70% of the patients are without attacks for a long period and are fully socially integrated. Epilepsy is clinically classified into generalized epilepsies; which are of symptomatic origin in 50% of the cases, and focal epilepsies, which are even more frequent caused by CNS-injuries. The diagnosis of epilepsy results from the synopsis of the clinical picture of the attack and the electro-encephalogram (EEG), in case of doubts from the analysis of the video-EEG. The anti-convulsive drug therapy is undertaken as long-term treatment when free of attacks for 3-5 years and has to be monitored clinically as well as biochemically. The option of epilepsy-surgical procedures in a center of epilepsy should be considered in cases of a resistance to drug therapy. The tight cooperation with the family physician is of great importance for the ambulant epileptic care, others like social service, careers guidance and psychologic service have to be integrated.

摘要

儿童癫痫的发病率为0.8%,是中枢神经系统最常见的慢性病之一。过去二十年中诊断和治疗方法的改进使得如今60%至70%的患者能够长期无发作,并完全融入社会。癫痫在临床上分为全身性癫痫,其中50%病例有症状性起源;以及局灶性癫痫,其更常由中枢神经系统损伤引起。癫痫的诊断基于发作的临床表现和脑电图(EEG)的概要,如有疑问则需分析视频脑电图。抗惊厥药物治疗作为长期治疗,在无发作3至5年时进行,并且必须进行临床和生化监测。对于药物治疗耐药的病例,应考虑在癫痫中心进行癫痫外科手术。与家庭医生的密切合作对于癫痫患者的门诊护理非常重要,还必须整合社会服务、职业指导和心理服务等其他方面。

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