Claes L, Hoellen I, Ignatius A
Abteilung Unfallchirurgische Forschung und Biomechanik, Universität Ulm.
Orthopade. 1997 May;26(5):459-62. doi: 10.1007/s001320050112.
Bone cements are used to treat compression fractures, fill bone defects and improve implant fixation in osteoporotic patients through reinforcement of weak bone. When the fracture repair is complete the bone cement ideally should degrade. In general, calcium-phosphate bone cements are biodegradable and can fulfill this temporary function. Several research groups have developed calcium-phosphate bone cements in the last years which have a chemical structure similar to that of the apatite of bone. However the conditions for processing the cement intraoperatively, as well as the mechanical properties and degradation characteristic of the various products show great variations. Clinical long-term studies have not yet been reported so far. Whether these new types of bone cements fulfill all the requirements for clinical application is still not certain and remains to be determined in future studies.
骨水泥用于治疗压缩性骨折、填充骨缺损,并通过增强骨质疏松患者的薄弱骨骼来改善植入物固定。当骨折修复完成时,理想情况下骨水泥应该降解。一般来说,磷酸钙骨水泥是可生物降解的,能够履行这种临时功能。在过去几年中,几个研究小组开发了化学结构与骨磷灰石相似的磷酸钙骨水泥。然而,术中处理骨水泥的条件以及各种产品的机械性能和降解特性差异很大。目前尚未有临床长期研究报告。这些新型骨水泥是否满足临床应用的所有要求仍不确定,有待未来研究确定。