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[牛的脑型李氏杆菌病:文献综述与个别病例回顾性分析]

[Cerebral listeriosis in cattle: literature review and retrospective analysis of individual cases].

作者信息

Hirsbrunner G, Nicolet J, Tontis A, Martig J

机构信息

Klinik für Nutztiere und Pferde, Universität Bern.

出版信息

Tierarztl Prax. 1997 Jul;25(4):336-43.

PMID:9312892
Abstract

Between 1990 and 1994, 89 cattle with signs of affection of the central nervous system were referred to the Clinic for Food Animals and Horses, University of Bern; in 17 cases of which, cerebral listeriosis was diagnosed. History, clinical, hematologic findings and cerebrospinal fluid analysis at admission were evaluated retrospectively. Four cattle were slaughtered after cerebral listeriosis had been diagnosed clinically because of economic reasons. Therapy, consisting of administration of penicillin (i.m./i.v.), intravenous fluids (including bicarbonate replacement), and oral fluids and rumen juice was initiated in the remaining 13 cases. Five of the 13 cattle were refractory to treatment and had to be euthanatized, one to two days after initiation of therapy. Clinical diagnosis of cerebral listeriosis was confirmed by histological examination of brain stem tissue in all nine cattle that were slaughtered or euthanatized; however, Listeria monocytogenes was isolated by standard culturing of brain stem tissue in two of these cases only. Eight to 62 months after discharge from the clinic, telephone interview with the owners of the surviving animals revealed that recovery had been uneventful and satisfactory in all of the eight cases.

摘要

1990年至1994年间,89头出现中枢神经系统感染症状的牛被转诊至伯尔尼大学食用动物与马诊所;其中17例被诊断为脑型李氏杆菌病。对入院时的病史、临床症状、血液学检查结果及脑脊液分析进行了回顾性评估。由于经济原因,4头牛在临床诊断为脑型李氏杆菌病后被屠宰。其余13头牛开始接受治疗,治疗方法包括注射青霉素(肌肉注射/静脉注射)、静脉输液(包括补充碳酸氢盐)以及口服液体和瘤胃液。13头牛中有5头对治疗无反应,在开始治疗后一至两天不得不实施安乐死。通过对所有9头被屠宰或实施安乐死的牛的脑干组织进行组织学检查,证实了脑型李氏杆菌病的临床诊断;然而,仅在其中2例中通过对脑干组织进行标准培养分离出了单核细胞增生李斯特菌。在这些动物出院8至62个月后,对存活动物的主人进行电话访谈发现,所有8例恢复过程均顺利且令人满意。

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